艾滋变异病毒在扩散


艾滋变异病毒在扩散

 
 
 
 
 

艾滋变异病毒在扩散
http://www.sina.com.cn  2009年03月01日03:01  都市快报
  据新华社 一个国际研究小组在最新一期《自然》杂志上报告说,因为基因变异而能躲避人免疫系统攻击的艾滋病病毒正在扩散。

  有美国哈佛大学的科学家和日本熊本大学研究人员参与的这个国际研究小组最近分析了日本、英国、南非等8个国家约2800个艾滋病病毒感染者,他们发现:和人组织相容性抗原结合的艾滋病病毒的蛋白质有14处发生了变异。

  有一些感染者先天有某种特定类型的人组织相容性抗原,其中,约96%的感染者的细胞内测出了变异的艾滋病病毒。没有特定抗原的感染者中有29%的人体内存在变异的艾滋病病毒。

  研究人员推测,有特定类型抗原的感染者体内,变异的艾滋病病毒不断增殖,能传播到不具备这种特定抗原的人体里。

  这个国际科学小组的主持人、美国哈佛大学免疫学家古尔德尔说:“以前,我们知道病毒会在单个患者身上演化、变异。对研制艾滋病疫苗来说,只要在大部分患者中的病毒不变,这就不是特别重要。”

  但是,现在的新发现意味着:“我们即使发现了有效的艾滋病疫苗,也可能需要按照病毒不断变异演化的情况,不断改变疫苗”。

 

Variation in the spread of HIV virus
03 years http://www.sina.com.cn 2009 on 01 Day 03:01 City Express
According to Xinhua News Agency, an international research team in the latest issue of "Nature" magazine reported that genetic variation, because people can evade the immune system to attack the AIDS virus is spreading.

Has the United States and Japan, scientists at Harvard University, Kumamoto University researchers involved in this international research team recently analyzed the Japan, the United Kingdom and South Africa about eight National 2800 HIV-infected persons, they found: and Human histocompatibility antigen combining HIV proteins have taken place in 14 variations.

Some infected people have innate has a particular type of person histocompatibility antigen, one of about 96% of the cells infected with a variation of inner HIV. No specific antigen has infected 29 percent of the human body exists in the variation of HIV.

The researchers speculated that the antigen has a specific type of infection in vivo, variation of constant proliferation of HIV, can spread to not have this particular antigen in the body.

The international scientific group's host, the United States古尔德尔immunologist at Harvard University, said: "In the past, we know that the virus will be in a single patient evolution, variation. To develop an AIDS vaccine, as long as in most patients with HIV do not change, it is not particularly important. "

But now, new findings mean that: "We even found an effective AIDS vaccine may also be required in accordance with the continuous variation of the evolution of the virus situation, changing the vaccine."