一种可以供女性自主使用的“杀微生物剂”将发挥和安全套的同等作用，能有效杀死艾滋病病毒，从而减缓艾滋病传播。

　　目前国际上已有产品进入三期临床试验阶段，中国也正在研究中。由世界卫生组织及南京大学公共健康医学中心联合主办的“杀微生物剂在中国的研究和开发”国际研讨会得出结论， “杀微生物剂其实是一种广谱杀菌剂，可以有效杀死艾滋病毒。但它最大的好处是可由女性自己使用，而不需要依靠伴侣。”

　　清华大学艾滋病综合研究中心常务副主任、中国医学科学院北京协和医学院艾滋病研究中心主任张教授解释说，中国从2006年、2007年开始，性传播已成为艾滋病毒传播的主要途径，我们通常呼吁通过使用安全套来降低传播风险，而杀微生物剂则可以通过女性放入阴道，有效杀死艾滋病病毒和性病病原体。

　　可以预见，杀微生物剂如果和安全套共同使用，艾滋病的传播风险也大大降低。不过目前杀微生物剂的研发面临着一些困难，最关键的技术难点是，既要能杀死艾滋病毒，又不能杀死身体本身存在的有益菌，还不能激活阴道表面细胞，否则反而会加快艾滋病毒感染。

　　南大公共健康医学中心主任吴稚伟是中国从事“杀微生物剂”研究的专家之一，他介绍说，目前国际上有一系列前期产品在研发，有的已进入临床一期、二期和三期，中国也在研究中，不过还没有建立规范的平台，仅在研究所中进行。 “其实，对艾滋病来说，最关键还是预防，一旦进入体内就无法彻底清除，目前所有药品只能暂时抑制。

　　而且对艾滋病疫苗的研究也非常艰难，可以说至今没什么突破进展。”作为国内研制艾滋病疫苗的权威专家张林琦无奈地说，艾滋病毒进入体内后，与身体的免疫系统会有一个长期的较量过程，最终让免疫系统丧失殆尽。

　　艾滋病毒是病毒中最狡猾的一种，隐蔽性极强，它会进入人体细胞，变成“内奸”，必须把感染病毒的细胞找到，才能有针对性。而当前的疫苗研究感觉有点“乱放箭”，却始终抓不到要害，没有诱导出抗艾滋病毒的有效反应，这也是目前最大的困惑。去年国际上亮相了几百种疫苗，有效的只有三四十种，进入临床三期的只有两种，而且效果还不好。(图片来源：PConline摄影部落)

The female condom does not necessarily kill the HIV virus
2010-12-08 09:16:38 Author: Unknown Source: 39 Health Net entry: fengshurong

Introduction: Despite the current knowledge about the spread of AIDS has been able to promote the well, but due to AIDS is not completely effective cure, so inevitably the mere mention all about! AIDS, there are some preventive measures, but you know, the female condom's role in this do?




A woman can be independent for the use of the "microbicide" will play the same role, and condoms can effectively kill the AIDS virus, thus slowing the spread of AIDS.

Existing products into the current international Phase III clinical trial stage, China is also being investigated. By the World Health Organization and Public Health, Nanjing University Medical Center jointly organized a "microbicide research and development in China," International seminar concludes, "Microbicides is a broad-spectrum fungicide, can effectively kill the HIV virus. but the biggest benefit is used by the women themselves, without the need to rely on partners. "

AIDS Research Center, Tsinghua University Deputy Director, Beijing Union Medical College Chinese Academy of Medical Sciences Director of the Center for AIDS Research Professor Zhang explained that China from 2006, 2007, sexual transmission has become the main way of HIV transmission, we usually called for the use of condoms to reduce the risk of transmission, and microbicides by women into the vagina can effectively kill the AIDS virus and sexually transmitted pathogens.

Can be expected, microbicides and condoms if used together, the risk of transmission of AIDS has also greatly reduced. However, the development of microbicides is currently facing some difficulties, the most critical technical problems that it is necessary to kill HIV, the body itself can not kill the beneficial bacteria present, cells can not activate the surface of the vagina, or instead will speed up HIV virus infection.

Director of Public Health South Medical Center is China's Wu Chih-wei in the "microbicide" of one of the experts, he said that at present there are a range of international products in early development, some have entered clinical Phase I, Phase II and III, China also being considered, but not to establish a standard platform, the Institute carried out only in the. "In fact, AIDS, the most critical is to prevent, once inside the body can not completely remove all current drugs only temporarily suppressed.

AIDS vaccine research but also very difficult to say so far no breakthroughs. "As the leading experts in AIDS vaccine development Zhang Linqi frustration that HIV enters the body, and the body's immune system process will have a long struggle, and ultimately lost the immune system.

HIV is a virus of the most cunning, concealed strong, it will enter human cells, into a "traitor" and must find the virus-infected cells, can be targeted. And the current vaccine research feels a bit "chaotic throw," he always grasp crucial, did not induce an effective response against HIV, which is currently the largest confusion. International debut last year, hundreds of types of vaccines effective only three or four ten, only two entered clinical Phase III, and the results are not good. (Source: PConline photography blog)