破解艾滋病毒增殖“钥匙”
http://www.huanqiu.com 来源：环球网
2009-03-12 09:56
日本研究人员在最新的美国《国家科学院学报》网络版上报告说，他们成功分析出艾滋病病毒增殖必需的蛋白酶整体构造。
此前研究发现艾滋病病毒增殖必需的蛋白酶分子中氢原子的位置对蛋白酶的作用能产生重要影响，但确定氢原子的具体位置非常困难。
来自日本原子能研究开发机构和京都药科大学等机构的研究人员首先制造了一种晶体，这种晶体由艾滋病病毒增殖必需的蛋白酶和能使之丧失功能的阻碍剂结合而成，然后研究人员借助穿透力强的中子射线通过分析晶体构造，了解到艾滋病病毒增殖必需的蛋白酶的整体结构，确定了蛋白酶分子中氢原子的位置。
研究人员认为，这次研究将有助于将来研发出更加有效的抗艾滋病药物。
HIV proliferation crack "key"
http://www.huanqiu.com Source: Global Net
2009-03-12 09:56
Japanese researchers in the latest American "National Academy of Sciences" on online version reported that they successfully analyze the proliferation of HIV protease necessary for the overall structure.
Previous study found that the proliferation of HIV protease molecules necessary for the location of hydrogen atoms on the role of proteases can have a major impact, but to determine the specific location of hydrogen atoms very difficult.
From Japan Atomic Energy Research and Development institutions and the Kyoto Pharmaceutical University researchers of institutions such as the first to create a crystal, this crystal by the AIDS virus protease and make the necessary loss of function of a combination of obstruction agent, then researchers with good penetration through the analysis of the neutron-ray crystal structure, that the proliferation of HIV protease necessary for the overall structure, identified the protease molecule hydrogen atom position.
The researchers believe that this study will contribute to the future to develop more effective anti-AIDS drugs.
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人类死因：艾滋病2012达顶峰
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人类死因：艾滋病2012达顶峰
http://www.51daifu.com日期：2009-03-11 13:45 来源：新浪科技 世卫组织预测人类死因 艾滋病2012达顶峰
据刚刚更新的世界卫生组织《全球疾病负担(global burden of disease)》报告，未来20年间抽烟的人数会不断增加，所以心脏病将继续扮演人类第一大杀手的角色，而艾滋病将在2012年达到顶峰，随后艾滋病患病人数将逐步下降。
这份报告对最近的人类死亡原因进行了对比，并着眼于全世界健康和安全趋势的变化情况。世界卫生组织通过这项研究结果，不仅可以告诉我们现在什么在不断夺走人们的生命，而且还可以告诉我们2030年人类的主要死亡原因。
世界卫生组织刚刚更新的《全球疾病负担》报告上的信息以2004年的研究资料为基础，对2030年疾病将如何对人口产生影响进行了预测。该报告预测的最有影响力的变化可能是，全球的传染病死亡率将大幅下降。2004年全球的第六大致死原因——艾滋病有望在2012年达到顶峰，2030年的排名降下至第十位。其他传染病的患病人数有望下降得更快。2004年第七大致死原因——肺结核的排名在2030年将下降至第23位。
传染病致死人数不断减少，意味着老龄化人口将不断增加，尤其在收入更低的国家，因为这些国家的人在老年阶段因患缺血性心脏病( ischemic heart disease)和癌症死亡的人数更多。但是全球的发展和行为改变也将对特定致死原因产生影响。世界卫生组织指出，中等收入和低收入国家的抽烟人数不断增加，将导致更多人死于心血管疾病、慢性肺炎和一些癌症。运输业快速发展和道路更加拥堵，将进一步助长交通事故致死人数的增加。
Human cause of death: AIDS in 2012 reached its peak
http://www.51daifu.com date :2009-03-11 13:45 Source: Sina Technology WHO prediction of human cause of death of AIDS reached its peak in 2012
According to the World Health Organization has just been updated, "the global burden of disease (global burden of disease)" report, the next 20 years the number of smokers will continue to increase, so heart disease will continue to play the largest killer of mankind's role, and AIDS in 2012 reached a peak, followed by AIDS will gradually decrease the number of patients.
The report on the recent human causes of death were compared, and focused on health and safety all over the world trend of Change. World Health Organization adopted the results of this study can not only tell what we are now constantly claimed the lives of people, but also tells us that in 2030 the leading cause of death of mankind.
World Health Organization has just updated the "global burden of disease" in order to report information on the 2004 research data based on the disease in 2030 will have an impact on how the population is predicted. The report forecasts the most influential change may be, the global mortality of infectious diseases will be substantially reduced. In 2004 the sixth largest global cause of death - AIDS is expected to peak in 2012, ranking down in 2030 to tenth place. Other infectious diseases is expected to decline in the number of patients faster. 2004, the seventh largest cause of death - pulmonary tuberculosis in 2030 at the ranking will drop to No. 23.
The number of infectious disease deaths are decreasing, implies that the aging population will continue to increase, particularly in lower income countries, because people in these countries at older ages due to ischemic heart disease (ischemic heart disease) and cancer deaths more . However, global development and behavioral change will also have an impact on the specific cause of death. World Health Organization points out that middle-income and low-income countries, the increasing number of smoking will lead to more people die of cardiovascular disease, chronic pneumonia and some cancers. The rapid development of transport and road congestion, it will further contribute to increase in the number of fatal traffic accidents.
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