AIDS gene therapy
Author: Source: Science Times publisher: Liu Bin Category: News Scan Date: 2009-06-24 Today View / Total View: 96/686

The first human AIDS virus (HIV) infection in patients with the results of clinical trials of gene therapy is finally out. Before the new results published in the online publication of "Nature - Medicine" journal. AIDS patients, gene therapy is an attractive option because of the one-time use of this therapy can reduce viral load, the protection of the immune system and avoid the life-long antiretroviral therapy use.

Ronald Mitsuyasu and colleagues on 74 HIV-infected adults implemented the randomized, double-blind, placebo-controlled clinical trial of gene conversion, or subjects receiving a placebo, or to accept carrying molecules called OZ1 blood stem cells, the molecular two HIV target protein in order to prevent viral replication. Throughout the course of clinical trials, OZ1 is safe, does not have any side effects. Despite the 47 weeks and 48 weeks of trial, to receive placebo OZ1 and viral load in the two groups were not statistically significant difference, but at 100 weeks, OZ1 group the number of CD4 + lymphocytes higher , and in patients, the lymphocytes were in addition to HIV.

New research shows that HIV-infected persons to the implementation of gene therapy is safe and effective, and this treatment can be developed into a general method to deal with AIDS.



AIDS gene therapy made significant progress in governance http://www.biotech.org.cn/news/news/show.php?id=67404
 
 
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Source: Science Times
Posted by: Bin