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药物鸡尾酒能扼制艾滋
2010-10-26 39健康网社区
38岁的美国妇女温妮有吸毒史，在使用污染的注射器时染上了艾滋病。她得知自己在5年以前就已经带有艾滋病(HIV)病毒。
个人预防艾滋病须知
温妮以及数千名病毒感染者很幸运，美国国家健康研究所的医生们开始使用由3种药物所组成的鸡尾酒，其中两种药物成分作用于逆转录酶，而第3种药物成分则抑制蛋白酶的活动。在这3种药物的作用下，患者的健康得到了改善。医生们以两种方法检查患者的病情是否真的好转。这两种指标叫做病毒负荷和CD4细胞数量。病毒负荷的意思是血液中的病毒数量。CD4细胞是免疫系统细胞，病毒把它们作为自身的繁殖地。CD4细胞具有保护人的机体不受外物侵害的功能。病毒负荷越大，CD4细胞遭受的侵害越多。这些CD4细胞的毁灭最终导致出现艾滋病的症状。换句话说是由偶然的感染发展成为恶性的病变，最终使人患上艾滋病。一个健康人每毫升的血液中有600到1200个CD4细胞，而一个人每毫升血液中大约200个CD4细胞，就可以视为艾滋病患者。当温妮开始服用药物鸡尾酒时，她的CD4细胞的数目是每毫升146个。这意味着她已经开始患上艾滋病了。用药6个月以后这个数量增加到了388个。
公务员詹姆斯58岁，1993年他被发现患有艾滋病。他的体重减轻了30磅至35磅。他的CD4细胞数量是10个或者20个，通常几乎就没有什么治愈的机会了。詹姆斯开始服用药物鸡尾酒后完全出乎意料，他的病情有了明显的好转，现在他的病毒负荷几近于零，CD4细胞的数量从9个增至188个。詹姆斯的情况并不少见。在美国，只需一个月的疗程就能奇迹般地减小患者的病毒负荷，血液中的病毒数量在30天内可从每毫升10万个降至不到200个。
但是从经验得知，病毒很有可能有朝一日复发。最新的报告表明，药物鸡尾酒也能够对付潜伏的HIV病毒。美国明尼苏达大学医药学院的科学家们给病人作了淋巴组织的活检，发现经过6个月药物鸡尾酒的疗程，就能杀死99.9%病毒。这使艾滋病患者看到了身体康复的希望。
2010-10-2639 Community Health Network
38-year-old American woman Winnie history of drug use, when in the use of contaminated syringes infected with AIDS. She learned that he had been in 5 years ago with AIDS (HIV) virus.
Personal Notes AIDS
Winnie and the thousands of HIV are lucky, the U.S. National Institutes of Health, the doctors started using the 3 drugs cocktail consisting of, two of which medicines act on reverse transcriptase, and the first three kinds of medicines are suppressed protease activity. In the role of 3 drugs, the patient's health improved. Doctors have two ways to check the condition of the patient is really better. These two indicators is called the viral load and CD4 cell count. Viral load means that the amount of virus in the blood. CD4 cells are immune system cells, the virus to them as their breeding grounds. CD4 cells in the human organism with protection against foreign objects from the function. The greater the viral load, CD4 cell suffered more abuse. The destruction of CD4 cells, eventually resulting in the symptoms of AIDS. In other words, by the chance of infection develop into malignant lesions, ultimately, suffering from AIDS. A healthy person per milliliter of blood in 600 to 1200 CD4 cells, and one about every 200 milliliters of blood CD4 cells, to be regarded as AIDS patients. When to start taking medication cocktails Winnie, her number of CD4 cells per milliliter of 146. This means that she has started to suffer from AIDS in the. 6 months after treatment increased the number of 388.
James, 58-year-old civil servant in 1993, he was found to have AIDS. He's lost weight 30-35 pounds. His CD4 cell count was 10 or 20, usually almost no chance of cure. James began taking the drug cocktails after the completely unexpected, his condition had improved significantly, and now he is close to zero viral load, CD4 cell count from 9 to 188. James is not uncommon. In the United States, just one month of treatment patients will be able to magically reduce the viral load, the amount of virus in the blood within 30 days from the 100,000 per milliliter to less than 200.
But from experience that one day the virus is likely to recur. The latest reports indicate that the drug cocktails are also able to deal with latent HIV. University of Minnesota School of Medicine scientists have made to the lymphoid tissue of the biopsy patients and found that after 6 months of treatment of drug cocktails, can kill 99.9% of the virus. This allows the body to see AIDS patients hope of recovery.
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